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Our results showed increased expression of fibroblast activation protein (FAP) together with markers of autophagy, inflammation, and oxidative stress in UF patients, which were all more markedly upregulated in obese compared to non-obese patients

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Metabolism 44:605610 [DOI] [PubMed] [Google Scholar] Kasa-Vubu JZ, Barkan A, Olton P, Meckmongkol T, Carlson NE, Foster CM 2002 Incomplete modified fast in obese early pubertal girls leads to an increase in 24-hour growth hormone concentration and a lessening of the circadian pattern in leptin

doi: 10.1186/alzrt146 [64] Hishikawa N, et al

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Perhaps this increase in OPC differentiation due to the presence of lactate can aid in remyelination by replacing the oligodendrocyte pool, which would warrant further investigation